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Building Medtech

Innotive Diagnostics is developing a novel bacterial infection diagnostic system to revolutionise the diagnosis of urinary tract infections (UTIs). Delivering a 99% reduction in time to result at the point of care using its diagnostic system vs. gold standard laboratory methods. Innotive’s technology is based on novel single-cell analysis that could be applicable across a range of bacterial infections. Visit website.

Every year, 4M new coronary stents are implanted to maintain the arteries’ functionality of patients who suffered a heart attack. However, 30% of these stents will fail within two years, and the sole method available to cardiologists to monitor stent malfunction is an angiogram—an invasive and ionizing procedure performed during surgery. We introduce the NIMBLE System, a first-in-class, non-invasive, non-ionizing microwave-based technology that enables cardiologists to obtain objective data about the status of coronary stents. This includes level of occlusion, potential fractures, or migrations that could endanger patients' lives. NIMBLE addresses a massive blue ocean market of $8 billion, allowing cardiologists to take control of their patients with heart failure, providing objective data through a convenient, non-invasive technology, aiming to save millions of lives. Visit website.

CAPS Medical (Israel) has developed a proprietary PlasmaSure technology that uses non thermal plasma to selectively target tumors through minimally invasive procedures. The PlasmaSure system uses existing minimally invasive tools and robotic systems, targeting a $100B TAM. CAPS effectively eliminates cancerous cells while preserving healthy tissue, allowing treatments to move from the operating room into a doctor's clinic. The technology is clinically tested and applicable to wide range of tumors. Visit website.

The Yacoub Heart Valve: A unique, tissue-engineered valve that promises to revolutionise heart valve replacement with no compromises. Using intricate scaffold technology that transforms in-situ into a living heart valve, using the body’s own healing processes to regenerate as nature intended. Restoring full life expectancy and in kids, adapting and growing. Visit website.

Njord is a medtech spin-off from Sahlgrenska University Hospital with a mission to solve unmet needs in radiology and patient handling. The first product launched is a novel patient transfer device (co-bot solution) Atle® 180 enabling improved efficiency and quality of care for acute care departments. The solution is already in use by +30 hospitals in Northern Europe. Visit website. 

Relief Srl is an innovative Italian MedTech company developing a first-in-class device for the treatment of stress urinary incontinence (SUI). Visit website.

Coramaze Technologies is developing an fast end effective solution for the treatment of tricuspid regurgitation. The TriPair system is deigned to be anchored atraumatically to the right atrium. The device is intended to be easily placed in a procedure taking less than twenty minutes, without the need for anesthesia or TEE. TriPair is agnostic of valve morphology and can be retrieved if necessary Visit website.

Planatome is a patented technology platform, adapted from semiconductor manufacturing and licensed to industry leaders to create the world’s most advanced surgical cutting instruments – think semiconductor meets medical. Visit website.

Clairity develops AI-driven tools to enhance breast cancer screening and risk assessment. Its platform utilizes deep learning models to analyze mammographic images, aiming to improve early detection, reduce racial and ethnic biases, and personalize care plans. The technology is grounded in decades of research led by Dr. Connie Lehman at institutions such as Mass General Brigham and MIT. Clairity's approach seeks to transform mammography from a one-size-fits-all model to a precision medicine framework. Visit website.

Transforming the experience for both patient and clinician in interventional procedures with a 3D augmented reality platform featuring real-time holographic visualization of the patient’s actual anatomy, “floating” over the patient. Visit website.

​Twinical develops digital twin technologies to enhance surgical planning and navigation in complex soft tissue procedures. Its platform creates high-fidelity 3D virtual replicas of patient organs, enabling surgeons to assess tumor locations and surgical complexity preoperatively. In the operating room, Twinical's augmented reality framework transforms these digital twins into transparent organ models, providing real-time anatomical insights and supporting robotic integration for improved safety and precision. Visit website.

The first osseointegrative biomimetic knee cartilage implant. Visit website.

Wellumio is a venture-backed company specializing in portable MRI solutions for acute neuroimaging applications. The company’s core enabling technology is a novel pulse-gradient free nuclear magnetic resonance sensor platform with an initial focus on acute stroke triage and diagnosis. Visit website.

Berlin Heals is developing the C-MIC system, an implantable electroceutical device that delivers a constant, but minimal, electrical direct current that mimics the physiological electrical currents produced by the heart. The device is a near-curative treatment for patients with heart failure that propagates the reverse remodeling of cardiac muscle tissue to restore heart function and size, thereby reducing the symptoms of heart failure and improving quality of life. Visit website.

SamanTree Medical's Histolog Scanner is a digital microscopy scanner for high-resolution imaging of the surface of fresh tissue. The device utilizes novel, ultra-fast confocal microscopy technology to enable rapid histological assessment in the operating room or pathology laboratory.  Visit website.

DeepSight Technology develops advanced medical imaging solutions using proprietary sensing technology to enhance diagnostic ultrasound capabilities. The company’s NeedleVue Technology is designed to improve ultrasound-assisted needle guidance, addressing challenges such as complex calibration, reduced sensitivity, and angle dependence. By integrating innovative sensor technology with interventional devices, NeedleVue enables real-time verification of device placement, aiming to reduce procedural uncertainty and streamline interventional workflows. DeepSight Technology operates from the San Francisco Bay Area and Clayton, Missouri, with a focus on expanding the range and effectiveness of diagnostic ultrasound. Visit website.

ConnCons integrates connectivity into infusion consumables to create a cloud to vessel end-to-end digital solution. The system enables safer, faster and automated therapies with a superior patient experience. First clinical applications are targeted at both center-based and home oncological therapy. Visit website.

INNITIUS develops a medical device that combines intravaginal hardware to measure cervical tissue consistency with shear elastic waves and machine learning algorithms. The device aims to provide diagnostics for multiple women’s health conditions related to childbirth timing, with dedicated algorithms for each specific indication Visit website.

Multi-organ failure (MOF) is the main cause of death on ICUs. The ADVOS therapy offers the first and only integrated solution for MOF and acidosis. It includes the support of the liver, lungs, and kidneys in a single device. Patient survival is significantly improved through simultaneous organ detoxification and acid-base balance management. The brand-new blood purification technology revolutionizes detoxification and enables blood pH correction for the first time. The complexities of managing multiple organ failures in a single organism is addressed with a single device. Visit website.

BrainSpace is developing a solution to simplify critical care in neurocritical patients. BrainSpace is committed to improving the way brain pressure is managed in patients recovering from stroke, traumatic brain injury, and neurosurgery. Currently patients requiring intracranial pressure management must be meticulously monitored and measured hourly by a nurse. The company has developed an automated monitoring solution as an alternative to the antiquated drainage monitoring relying on a manometer-based drain and blood pressure monitor that eliminates the hassle for patients and providers while improving the quality of data being captured for researchers and physicians. Visit website.

Calla Lily Clinical Care is a women's health focused company which has developed the proprietary Callavid® platform for intravaginal drug delivery. Initial target indications are in IVF and miscarriage prevention, followed by delivery of live biotherapeutics (LBPs) to reduce antibiotic usage which contributes to antimicrobial resistance (AMR). Further use-cases include effective sample collection to facilitate the next generation of biomarker-based diagnostic tests for endometriosis and a wide range of other conditions. Visit website.

BioAro is a biotechnology company specializing in genomics, artificial intelligence and blockchain technologies. The company offers whole genome sequencing, microbiome testing, and software solutions to support clinical testing offerings and improve overall efficiency of healthcare practices. Visit website.

Solenic Medical is developing a non-invasive medical device that utilizes alternating magnetic fields to eradicate biofilms that form on implants. The company's platform uses external magnetic coils to destroy infective biofilms on the surface of knee and hip replacement implants, as well as plates and rods for trauma related procedures. Solenic's solution is being developed to replace the expensive and risky two-step revision surgery, which is the current standard of care for chronic infections on medical implants. Visit website.

Locate Bio is working to solve some of the most complex degenerative and infectious diseases that affect the muscular skeletal system. Locate utilises Programmed Drug Release to re-align the bioavailability of existing drugs with the underlying biological need. This bio-optimisation step has demonstrated break through improvements in performance in preclinical testing. Locate Bio’s lead product, LDGraft, is entering human clinical studies next year, for the treatment of chronic lower back pain caused by degenerative disc disease. CognitOss Gel is in developed to overcome bacterial biofilm infections around non-viable tissue and orthopaedic implants. Visit website.